Growth Hormone R Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58925

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP2-58925
NBP2-58925-25ul
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Growth Hormone R/GHR Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: NWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMSQF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Growth Hormone R Antibody

Immunohistochemistry-Paraffin: Growth Hormone R Antibody [NBP2-58925]

Immunohistochemistry-Paraffin: Growth Hormone R Antibody [NBP2-58925]

Immunohistochemistry-Paraffin: Growth Hormone R Antibody [NBP2-58925] - Staining in human liver and lymph node tissues using anti-GHR antibody. Corresponding GHR RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Growth Hormone R Antibody [NBP2-58925]

Immunohistochemistry-Paraffin: Growth Hormone R Antibody [NBP2-58925]

Immunohistochemistry-Paraffin: Growth Hormone R Antibody [NBP2-58925] - Staining of human liver shows high expression.
Immunohistochemistry-Paraffin: Growth Hormone R Antibody [NBP2-58925]

Immunohistochemistry-Paraffin: Growth Hormone R Antibody [NBP2-58925]

Immunohistochemistry-Paraffin: Growth Hormone R Antibody [NBP2-58925] - Staining of human lymph node shows low expression as expected.

Applications for Growth Hormone R Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Growth Hormone R/GHR

Growth hormone receptor encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized.

Long Name

Growth Hormone Receptor

Alternate Names

GHR

Gene Symbol

GHR

Additional Growth Hormone R/GHR Products

Product Documents for Growth Hormone R Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Growth Hormone R Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.