GTP-binding protein 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-29551

Novus Biologicals, part of Bio-Techne
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NBP3-29551
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Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GTP-binding protein 1 Antibodies »

Product Specifications

Immunogen

Between 575 and 625

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GTP-binding protein 1 Antibody

GTP-binding protein 1 Antibody

Immunoprecipitation:GTP-binding protein 1 AntibodyNBP3-29551] -

Immunoprecipitation:GTP-binding protein 1 AntibodyNBP3-29551] -Detection of human GTPBP1 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-GTPBP1 antibody NBP3-29551 (lot NBP3-29551-1) used for IP at 6 µg per reaction. GTPBP1 was also immunoprecipitated by rabbit anti-GTPBP1.. For blotting immunoprecipitated GTPBP1, NBP3-29551 was used at 0.4 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

Applications for GTP-binding protein 1 Antibody

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: GTP-binding protein 1

GTPBP1, also known as GTP-binding protein 1, is a 669 amino acid that is approx. 72 kDa, stimulates degradation of target mRNA species, binds GTP, is important for the regulation of circadian mRNA stability, and has GTPase activity. Studies on this protein have shown a relationship with the following disorders and diseases: lassa fever, fragile x syndrome, lymphocytic choriomeningitis, antiphospholipid syndrome, lupus erythematosus, adenoma, and interferon. This protein interacts with EXOSC2/RRP4, EXOSC3/RRP40, EXOSC5/RRP46, HNRNPD, HNRNPR, SYNCRIP, LRP1, SQSTM1, ABCF1, and MAP1LC3B in GTP catabolic process, positive regulation of mRNA catabolic process, signal transduction, and immune response pathways.

Alternate Names

GP1GTP-binding protein 1, GP-1MGC20069, G-protein 1, GTP binding protein 1, HSPC018

Gene Symbol

GTPBP1

Additional GTP-binding protein 1 Products

Product Documents for GTP-binding protein 1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GTP-binding protein 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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