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Guanylyl Cyclase alpha 1 Antibody (2H1)

Novus Biologicals, part of Bio-Techne | Catalog # H00002982-M01

Novus Biologicals, part of Bio-Techne
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H00002982-M01

Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 2H1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

GUCY1A3 (AAH28384, 41 a.a. ~ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KATMPICQDIPEKNIQESLPQRKTSRSRVYLHTLAESICKLIFPEFERLNVALQRTLAKHKIKESRKSLEREDFEKTIAEQAVAAGVPVEVIKESLGEEV

Specificity

GUCY1A3 (2H1)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Guanylyl Cyclase alpha 1 Antibody (2H1)

Sandwich ELISA: Guanylyl Cyclase alpha 1 Antibody (2H1) [H00002982-M01] - Detection limit for recombinant GST tagged GUCY1A3 is approximately 1ng/ml as a capture antibody.

Applications for Guanylyl Cyclase alpha 1 Antibody (2H1)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Guanylyl Cyclase alpha 1

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit, such as alpha-1 (GUCY1A3), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM]

Long Name

Guanylate cyclase soluble subunit alpha-1

Alternate Names

EC 4.6.1.2, GCS-alpha-1, GCS-alpha-3, GUC1A3, GUCSA3, GUCY1A1, GUCY1A3

Entrez Gene IDs

2982 (Human)

Gene Symbol

GUCY1A1

OMIM

139396 (Human)

Additional Guanylyl Cyclase alpha 1 Products

Product Documents for Guanylyl Cyclase alpha 1 Antibody (2H1)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Guanylyl Cyclase alpha 1 Antibody (2H1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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