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Guanylyl Cyclase alpha 1 Antibody (SR2180)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22388

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
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NBP3-22388-100ul
NBP3-22388-50ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2180

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Guanylyl Cyclase alpha 1 Antibody (SR2180)

Immunogen

A synthesized peptide derived from human Guanylyl Cyclase alpha 1 (Uniprot #: Q02108)

Specificity

Detects endogenous levels of total Guanylyl Cyclase alpha 1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

73 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Guanylyl Cyclase alpha 1 Antibody (SR2180)

Western Blot: Guanylyl Cyclase alpha 1 Antibody (SR2180) [NBP3-22388] -

Western Blot: Guanylyl Cyclase alpha 1 Antibody (SR2180) [NBP3-22388] - Western blot analysis using NBP3-22388 in Human fetal kidney lysate.

Applications for Guanylyl Cyclase alpha 1 Antibody (SR2180)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Guanylyl Cyclase alpha 1

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit, such as alpha-1 (GUCY1A3), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM]

Long Name

Guanylate cyclase soluble subunit alpha-1

Alternate Names

EC 4.6.1.2, GCS-alpha-1, GCS-alpha-3, GUC1A3, GUCSA3, GUCY1A1, GUCY1A3

Gene Symbol

GUCY1A1

Additional Guanylyl Cyclase alpha 1 Products

Product Documents for Guanylyl Cyclase alpha 1 Antibody (SR2180)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Guanylyl Cyclase alpha 1 Antibody (SR2180)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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