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Guanylyl Cyclase alpha 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16770

Novus Biologicals, part of Bio-Techne
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NBP2-16770

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (96%), Canine (98%), Mouse (97%), Porcine (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human Guanylyl Cyclase alpha 1. The exact sequence is proprietary.

Reactivity Notes

Zebrafish (83%), Japanese Medaka (80%).

Localization

Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

77 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Guanylyl Cyclase alpha 1 Antibody

Western Blot: Guanylyl Cyclase alpha 1 Antibody [NBP2-16770]

Western Blot: Guanylyl Cyclase alpha 1 Antibody [NBP2-16770]

Western Blot: Guanylyl Cyclase alpha 1 Antibody [NBP2-16770] - Sample (30 ug of whole cell lysate) A: 293T 7. 5% SDS PAGE gel, diluted at 1:1000.

Applications for Guanylyl Cyclase alpha 1 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Guanylyl Cyclase alpha 1

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit, such as alpha-1 (GUCY1A3), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM]

Long Name

Guanylate cyclase soluble subunit alpha-1

Alternate Names

EC 4.6.1.2, GCS-alpha-1, GCS-alpha-3, GUC1A3, GUCSA3, GUCY1A1, GUCY1A3

Gene Symbol

GUCY1A1

UniProt

Additional Guanylyl Cyclase alpha 1 Products

Product Documents for Guanylyl Cyclase alpha 1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Guanylyl Cyclase alpha 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.