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GUCY2C Antibody (indusatumab)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28313

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # indusatumab

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

GUCY2C

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Endotoxin Level

< 0.001EU/ug,determined by LAL method.

Description

Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'indusatumab'.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Scientific Data Images for GUCY2C Antibody (indusatumab)

GUCY2C Antibody (indusatumab)

ELISA: GUCY2C Antibody (indusatumab)[NBP3-28313] -

Immobilized human GUCY2C His at 2 ug/mL can bind GUCY2C Antibody (indusatumab), EC50=0.00818 ug/mL.
GUCY2C Antibody (indusatumab)

Flow Cytometry: GUCY2C Antibody (indusatumab)[NBP3-28313] -

Human GUCY2C HEK293 cells were stained with GUCY2C Antibody (indusatumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS.

Applications for GUCY2C Antibody (indusatumab)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Guanylyl Cyclase C/GUCY2C

Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin.

Alternate Names

DIAR6, GC-C, GCC, Guanylate Cyclase C, GUC2C, GUCY2C, MUCIL, STA Receptor, StAR

Gene Symbol

GUCY2C

UniProt

Additional Guanylyl Cyclase C/GUCY2C Products

Product Documents for GUCY2C Antibody (indusatumab)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GUCY2C Antibody (indusatumab)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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