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GUCY2F Antibody - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-04892

Novus Biologicals, part of Bio-Techne
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NBP3-04892-100ul
NBP3-04892-20ul

Key Product Details

Species Reactivity

Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide and BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 250-460 of human GUCY2F (NP_001513.2). HSALIGGETQMHLLECAHDLKMTDGTYVFVPYDALLYSLPYKHTPYRVLRNNPKLREAYDAVLTITVESQEKTFYQAFTEAAARGEIPEKLEFDQVSPLFGTIYNSIYFIAQAMNNAMKENGQAGAASLVQHSRNMQFHGFNQLMRTDSNGNGISEYVILDTNLKEWELHSTYTVDMEMELLRFGGTPIHFPGGRPPRADAKCWFAEGKIC

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

124 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GUCY2F Antibody - Azide and BSA Free

Western Blot: GUCY2F AntibodyAzide and BSA Free [NBP3-04892]

Western Blot: GUCY2F AntibodyAzide and BSA Free [NBP3-04892]

Western Blot: GUCY2F Antibody [NBP3-04892] - Analysis of extracts of mouse eye, using GUCY2F antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit .

Applications for GUCY2F Antibody - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS with 50% glycerol, pH7.3.

Format

Azide and BSA Free

Preservative

0.01% Thimerosal

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Guanylyl Cyclase F/GUCY2F

The GUCY2F gene encodes a retinal guanylyl cyclase 2 single-pass type 1 membrane protein that plays a significant functional role in the rods and cones of photoreceptors. Its coded proteins are 1,108 amino acids long at a mass of approximately 124 kDA. It is thought to be involved in the resynthesis of cGMP which is required for recovery of a dark state after light activation of the visual signal transduction cascade (phototransduction). The GUCY2F gene participates is purine metabolism, relaxin pathway, phototransduction, and the CRHR pathway. Its known to interact with various genes such as GUCA1B, GUCA1A, GUCA1C, PDE11A, and PDE4A.

Long Name

Guanylate Cyclase 2F, Retinal

Alternate Names

CYGF, GC-F, GUC2DL, GUCY2F, ROS-GC2

Gene Symbol

GUCY2F

Additional Guanylyl Cyclase F/GUCY2F Products

Product Documents for GUCY2F Antibody - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GUCY2F Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov