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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunoblotting, Knockdown Validated

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 575 and 625 of human GW182/glycine-tryptophan protein of 182 kDa (NP_055309.2).

Reactivity Notes

Mouse reactivity reported in (PMID: 29935344).

Marker

P/GW Body Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for GW182 Antibody [DyLight 488]

Application
Recommended Usage

Immunoblotting

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GW182

GW182 (glycine-tryptophan protein of 182 kDa) is a member of the trinucleotide repeat containing 6 protein family. It functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. GW182 has been found to associate with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibition of GW182 expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.

Alternate Names

CAG repeat protein 26, CAGH26FLJ22043, DKFZp666E117, EMSY interactor protein, Glycine-tryptophan protein of 182 kDa, GW182 autoantigen, GW182GW1, KIAA1460EDIE, MGC75384, Protein GW1, TNRC6, trinucleotide repeat containing 6, trinucleotide repeat containing 6A, trinucleotide repeat-containing gene 6A protein

Gene Symbol

TNRC6A

Additional GW182 Products

Product Documents for GW182 Antibody [DyLight 488]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GW182 Antibody [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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