GW182 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88231

Novus Biologicals, part of Bio-Techne
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NBP1-88231
NBP1-88231-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GW182 Antibodies »

Product Summary for GW182 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QLQRLLAQQQRAQSQRSVPSGNRPQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMPHTTPELQKGPSPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWT

Marker

P/GW Body Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GW182 Antibody

Immunohistochemistry-Paraffin: GW182 Antibody [NBP1-88231]

Immunohistochemistry-Paraffin: GW182 Antibody [NBP1-88231]

Immunohistochemistry-Paraffin: GW182 Antibody [NBP1-88231] - Staining of human prostate shows strong nuclear combined with weaker granular cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: GW182 Antibody [NBP1-88231]

Immunohistochemistry-Paraffin: GW182 Antibody [NBP1-88231]

Immunohistochemistry-Paraffin: GW182 Antibody [NBP1-88231] - Staining of human endometrium shows strong nuclear and moderate cytoplasmic immunoreactivity in glandular cells.
Immunohistochemistry-Paraffin: GW182 Antibody [NBP1-88231]

Immunohistochemistry-Paraffin: GW182 Antibody [NBP1-88231]

Immunohistochemistry-Paraffin: GW182 Antibody [NBP1-88231] - Staining of human kidney shows strong nuclear and moderate cytoplasmic positivity in cells in tubules.
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Applications for GW182 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GW182

GW182 (glycine-tryptophan protein of 182 kDa) is a member of the trinucleotide repeat containing 6 protein family. It functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. GW182 has been found to associate with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibition of GW182 expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.

Alternate Names

CAG repeat protein 26, CAGH26FLJ22043, DKFZp666E117, EMSY interactor protein, Glycine-tryptophan protein of 182 kDa, GW182 autoantigen, GW182GW1, KIAA1460EDIE, MGC75384, Protein GW1, TNRC6, trinucleotide repeat containing 6, trinucleotide repeat containing 6A, trinucleotide repeat-containing gene 6A protein

Gene Symbol

TNRC6A

Additional GW182 Products

Product Documents for GW182 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GW182 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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