HAX-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28796

Novus Biologicals, part of Bio-Techne
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NBP1-28796
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Key Product Details

Species Reactivity

Human

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all HAX-1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-TRHEADSSPRGDPES corresponding to internal region according to NP_006109.2, NP_001018238.1.

Epitope

internal region

Specificity

This antibody is expected to recognize both reported isoforms (NP_006109.2 and NP_001018238.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for HAX-1 Antibody

Western Blot: HAX-1 Antibody [NBP1-28796]

Western Blot: HAX-1 Antibody [NBP1-28796]

Western Blot: HAX-1 Antibody [NBP1-28796] - (1ug/ml) Analysis of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for HAX-1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:2000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 33 kDa band observed in human kidney, liver and testis lysates (calculated MW of 31.6 kDa band according to NP_006109.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: HAX-1

The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

HCLS1 associated protein X-1

Alternate Names

HAX1, HCLSBP1, HS1BP1, SCN3

Entrez Gene IDs

10456 (Human)

Gene Symbol

HAX1

UniProt

NP_006109.2 (Human)

Additional HAX-1 Products

Product Documents for HAX-1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HAX-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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