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HAX-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49169

Novus Biologicals, part of Bio-Techne
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NBP2-49169
NBP2-49169-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: HQPRIFGGVLESDARSESPQPAPDWGSQRPFHRFDDVWPMDPHPRTREDNDLDSQVSQEGL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HAX-1 Antibody

Immunohistochemistry-Paraffin: HAX-1 Antibody [NBP2-49169]

Immunohistochemistry-Paraffin: HAX-1 Antibody [NBP2-49169]

Immunohistochemistry-Paraffin: HAX-1 Antibody [NBP2-49169] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: HAX-1 Antibody [NBP2-49169]

Immunohistochemistry-Paraffin: HAX-1 Antibody [NBP2-49169]

Immunohistochemistry-Paraffin: HAX-1 Antibody [NBP2-49169] - Staining of human rectum shows moderate to strong granular cytoplasmic positivity in glandular cells and a subset of leukocytes.
Immunohistochemistry-Paraffin: HAX-1 Antibody [NBP2-49169]

Immunohistochemistry-Paraffin: HAX-1 Antibody [NBP2-49169]

Immunohistochemistry-Paraffin: HAX-1 Antibody [NBP2-49169] - Staining of human tonsil shows strong cytoplasmic positivity in non-germinal center cells.

Applications for HAX-1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HAX-1

HAX1 is encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

HCLS1 associated protein X-1

Alternate Names

HAX1, HCLSBP1, HS1BP1, SCN3

Gene Symbol

HAX1

Additional HAX-1 Products

Product Documents for HAX-1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HAX-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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