HCLS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-30953

Novus Biologicals, part of Bio-Techne
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NBP1-30953
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (93%), Chicken (92%), Monkey (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HCLS1 Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human HCLS1. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rhesus Monkey (100%).

Localization

Membrane, Peripheral membrane protein (Probable) , Cytoplasm (Probable) , Mitochondrion

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HCLS1 Antibody

Western Blot: HCLS1 Antibody [NBP1-30953]

Western Blot: HCLS1 Antibody [NBP1-30953]

Western Blot: HCLS1 Antibody [NBP1-30953] - Sample (30 ug of whole cell lysate) A: Jurkat B: HL-60 7. 5% SDS PAGE; antibody diluted at 1:10000.
Immunohistochemistry-Paraffin: HCLS1 Antibody [NBP1-30953]

Immunohistochemistry-Paraffin: HCLS1 Antibody [NBP1-30953]

Immunohistochemistry-Paraffin: HCLS1 Antibody [NBP1-30953] - Paraffin-embedded Lymphocytes in gastric epithelium, using antibody at 1:100 dilution.
Western Blot: HCLS1 Antibody [NBP1-30953]

Western Blot: HCLS1 Antibody [NBP1-30953]

Western Blot: HCLS1 Antibody [NBP1-30953] - Sample (30 ug of whole cell lysate) A: NIH-3T3 B: JC 7. 5% SDS PAGE; antibody diluted at 1:5000.

Applications for HCLS1 Antibody

Application
Recommended Usage

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:5000-1:20000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HCLS1

Hematopoietic cell specific Lyn substrate 1 (HCLS1) is an intracellular protein involved in the signal transduction pathways in B and T lymphocytes. HCLS1 Tyr phosphorylation catalyzed by Syk and Lyn plays a crucial role in the translocation of the protein to the membrane and is involved in the cytoskeleton rearrangement triggered by thrombin in human platelets. The gene is a substrate for caspase cleavage during apoptosis.

Long Name

Hematopoietic Cell-specific Lyn Substrate 1

Alternate Names

Cortactin-like, CTTNL, LckBP1

Gene Symbol

HCLS1

Additional HCLS1 Products

Product Documents for HCLS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HCLS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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