HDAC6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-82212

Novus Biologicals, part of Bio-Techne
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NBP1-82212
NBP1-82212-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Histone Deacetylase 6/HDAC6 Antibodies »

Product Summary for HDAC6 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HDAC6 Antibody

Immunocytochemistry/ Immunofluorescence: HDAC6 Antibody [NBP1-82212]

Immunocytochemistry/ Immunofluorescence: HDAC6 Antibody [NBP1-82212]

Immunocytochemistry/Immunofluorescence: HDAC6 Antibody [NBP1-82212] - Staining of human cell line U-251MG shows positivity in nucleus but not nucleoli.
Immunohistochemistry-Paraffin: HDAC6 Antibody [NBP1-82212]

Immunohistochemistry-Paraffin: HDAC6 Antibody [NBP1-82212]

Immunohistochemistry-Paraffin: HDAC6 Antibody [NBP1-82212] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts and Leydig cells.

Applications for HDAC6 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Histone Deacetylase 6/HDAC6

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Long Name

Histone Deacetylase 6

Alternate Names

CPBHM, FLJ16239, HD6, HDAC6, JM21, PPP1R90

Gene Symbol

HDAC6

Additional Histone Deacetylase 6/HDAC6 Products

Product Documents for HDAC6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HDAC6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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