HECTD1 Antibody (1C7)

Novus Biologicals, part of Bio-Techne | Catalog # H00025831-M08

Novus Biologicals, part of Bio-Techne
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H00025831-M08
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 1C7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HECTD1 Antibodies »

Product Specifications

Immunogen

HECTD1 (NP_056197, 3 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. DVDPDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLDVSAECTRRIVGVDGAIKALCNRLVVVE

Specificity

HECTD1 - HECT domain containing 1 (1C7)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for HECTD1 Antibody (1C7)

Western Blot: HECTD1 Antibody (1C7) [H00025831-M08]

Western Blot: HECTD1 Antibody (1C7) [H00025831-M08]

Western Blot: HECTD1 Antibody (1C7) [H00025831-M08] - Detection against Immunogen (37.62 KDa) .

Applications for HECTD1 Antibody (1C7)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: HECTD1

The HECTD1 gene encodes a2, 610 amino acid long, 298 kDA E3 ubiquitin-protein ligase HECTD1 protein that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester. It then directly transmits the ubiquitin to targeted substrates and may be essential for development of the head mesenchyme and neural tube closure. HECTD1 interacts in interferon signaling and cytokine signaling in the immune system and is known to interact with various genes such as NME2, ERCC2, PITX2, CCNA2, and NME1-NME2. HECTD1 has been investigated in many diseases such as angelman syndrome, teratoma, carcinoma, malaria, and influenza.

Alternate Names

E3 ligase for inhibin receptor, E3 ubiquitin-protein ligase HECTD1, EC 6.3.2.-, EULIR, HECT domain containing 1, HECT domain-containing protein 1, KIAA1131FLJ38315

Entrez Gene IDs

25831 (Human)

Gene Symbol

HECTD1

UniProt

NP_056197 (Human)

Additional HECTD1 Products

Product Documents for HECTD1 Antibody (1C7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HECTD1 Antibody (1C7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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