Hematopoietic Prostaglandin D Synthase/HPGDS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-97022

Novus Biologicals, part of Bio-Techne
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NBP2-97022-100ul
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Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Hematopoietic Prostaglandin D Synthase/HPGDS Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with purified, recombinant Human Hematopoietic Prostaglandin D Synthase/HPGDS (Uniprot#: O60760; Met1-Leu199)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Applications for Hematopoietic Prostaglandin D Synthase/HPGDS Antibody

Application
Recommended Usage

ELISA

1:1000-1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Hematopoietic Prostaglandin D Synthase/HPGDS

Prostaglandin D synthase catalyzes the isomerization of PGH2 to produce PGD2. Prostaglandin D synthase induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGD synthase have been identified, namely the lipocalin type enzyme (b-trace) and the hematopoietic enzyme. Lipocalin type prostaglandin D synthase is localized in the central nervous system and male genital organs of various mammals and the human heart. This enzyme has been identified as b-trace, which is a major protein in human cerebrospinal fluid. Hematopoietic prostaglandin D synthase is widely distributed in the peripheral tissues and is localized in the antigen-presenting cells, mast cells, and megakaryocytes. This enzyme, which requires glutathione for activity, belongs to the sigma-class of glutathione-S-transferases.

Alternate Names

GSTS, PGDS, PTGDS2

Gene Symbol

HPGDS

Additional Hematopoietic Prostaglandin D Synthase/HPGDS Products

Product Documents for Hematopoietic Prostaglandin D Synthase/HPGDS Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Hematopoietic Prostaglandin D Synthase/HPGDS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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