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Hemoglobin A2 Antibody (rHBA/9167) [Janelia Fluor® 669]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24089JF669

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-24089JF669

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Janelia Fluor 669

Antibody Source

Recombinant Monoclonal Mouse IgG2b Kappa Clone # rHBA/9167

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Hemoglobin A2 Antibody (rHBA/9167) [Janelia Fluor® 669]

Immunogen

Recombinant fragment (around aa1-100) of human Hemoglobin A2 protein (exact sequence is proprietary)

Localization

Extracellular space.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for Hemoglobin A2 Antibody (rHBA/9167) [Janelia Fluor® 669]

Application
Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Hemoglobin A2

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta -pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) codingsequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but theydiffer significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA,which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains toconstitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemiasresult from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alphathalassemias have also been reported. (provided by RefSeq)

Alternate Names

alpha globin, alpha-2 globin, alpha-globin, Hemoglobin alpha chain, hemoglobin subunit alpha, hemoglobin, alpha 2

Gene Symbol

HBA2

Additional Hemoglobin A2 Products

Product Documents for Hemoglobin A2 Antibody (rHBA/9167) [Janelia Fluor® 669]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Hemoglobin A2 Antibody (rHBA/9167) [Janelia Fluor® 669]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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