HISPPD1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38368

Novus Biologicals, part of Bio-Techne
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NBP2-38368
NBP2-38368-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HISPPD1 Antibodies »

Product Summary for HISPPD1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: AKGCEEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHRKSPLPRSRKTATND

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HISPPD1 Antibody

Immunocytochemistry/ Immunofluorescence: HISPPD1 Antibody [NBP2-38368]

Immunocytochemistry/ Immunofluorescence: HISPPD1 Antibody [NBP2-38368]

Immunocytochemistry/Immunofluorescence: HISPPD1 Antibody [NBP2-38368] - Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
Immunohistochemistry: HISPPD1 Antibody [NBP2-38368]

Immunohistochemistry: HISPPD1 Antibody [NBP2-38368]

Immunohistochemistry: HISPPD1 Antibody [NBP2-38368] - Staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.

Applications for HISPPD1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HISPPD1

Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 (PubMed 17690096)).(supplied by OMIM)

Alternate Names

diphosphoinositol pentakisphosphate kinase 2FLJ21506, EC 2.7.4.21, EC 2.7.4.24, HISPPD1histidine acid phosphatase domain containing 1, Histidine acid phosphatase domain-containing protein 1, hsVIP2, inositol heptaphosphate kinase 2, inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2, InsP6 and PP-IP5 kinase 2, KIAA0433FLJ23463, VIP1 homolog 2, VIP2IP7K2

Gene Symbol

PPIP5K2

UniProt

O43314 (Human)

Additional HISPPD1 Products

Product Documents for HISPPD1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HISPPD1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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