Histamine H2R Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86082

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-86082
NBP1-86082-25ul
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Histamine H2 R Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: NRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR

Reactivity Notes

Mouse reactivity reported in the scientific literature (PMID: 26907350).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Histamine H2R Antibody

Immunohistochemistry-Paraffin: Histamine H2R Antibody [NBP1-86082]

Immunohistochemistry-Paraffin: Histamine H2R Antibody [NBP1-86082]

Immunohistochemistry-Paraffin: Histamine H2R Antibody [NBP1-86082] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: Histamine H2R Antibody [NBP1-86082]

Immunohistochemistry-Paraffin: Histamine H2R Antibody [NBP1-86082]

Immunohistochemistry-Paraffin: Histamine H2R Antibody [NBP1-86082] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: Histamine H2R Antibody [NBP1-86082]

Immunohistochemistry-Paraffin: Histamine H2R Antibody [NBP1-86082]

Immunohistochemistry-Paraffin: Histamine H2R Antibody [NBP1-86082] - Staining of human prostate shows strong cytoplasmic positivity in smooth muscle cells.
View 1 more images

Applications for Histamine H2R Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
IHC-P reported in scientific literature (PMID: 26907350). For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reviewed Applications

Read 2 reviews rated 4 using NBP1-86082 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Histamine H2 R

HRH2 encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

Long Name

Histamine H2 Receptor

Alternate Names

Gastric Receptor 1, Histamine H2R, HRH2

Gene Symbol

HRH2

Additional Histamine H2 R Products

Product Documents for Histamine H2R Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Histamine H2R Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.