Histamine N-Methyltransferase/HNMT Antibody (2G24)

Novus Biologicals, part of Bio-Techne | Catalog # H00003176-M12-50ug

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Kappa Clone # 2G24

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Histamine N-Methyltransferase/HNMT Antibodies »

Product Specifications

Immunogen

HNMT (NP_008826, 184 a.a. ~ 292 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3 Kappa

Scientific Data Images for Histamine N-Methyltransferase/HNMT Antibody (2G24)

Western Blot: Histamine N-Methyltransferase/HNMT Antibody (2G24) [H00003176-M12-50ug]

Western Blot: Histamine N-Methyltransferase/HNMT Antibody (2G24) [H00003176-M12-50ug]

Western Blot: Histamine N-Methyltransferase/HNMT Antibody (2G24) [H00003176-M12-50ug] - Detection against Immunogen (37.73 KDa) .
ELISA: Histamine N-Methyltransferase/HNMT Antibody (2G24) [H00003176-M12-50ug]

ELISA: Histamine N-Methyltransferase/HNMT Antibody (2G24) [H00003176-M12-50ug]

ELISA: Histamine N-Methyltransferase/HNMT Antibody (2G24) [H00003176-M12-50ug] - Detection limit for recombinant GST tagged HNMT is 0.1 ng/ml as a capture antibody.

Applications for Histamine N-Methyltransferase/HNMT Antibody (2G24)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Histamine N-Methyltransferase/HNMT

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Long Name

Histamine N-Methyltransferase

Alternate Names

Histamine NMethyltransferase, HMT, HNMT, HNMT-S1, HNMT-S2

Entrez Gene IDs

3176 (Human)

Gene Symbol

HNMT

OMIM

600807 (Human)

UniProt

NP_008826 (Human)

Additional Histamine N-Methyltransferase/HNMT Products

Product Documents for Histamine N-Methyltransferase/HNMT Antibody (2G24)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Histamine N-Methyltransferase/HNMT Antibody (2G24)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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