Histone H1.2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-87570

Novus Biologicals, part of Bio-Techne
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NBP2-87570
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Key Product Details

Species Reactivity

Human

Applications

Chromatin Immunoprecipitation (ChIP), Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all Histone H1.2 Antibodies »

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human Histone H1.2. Peptide sequence: ASGSFKLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKS The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for Histone H1.2 Antibody

Western Blot: Histone H1.2 Antibody [NBP2-87570]

Western Blot: Histone H1.2 Antibody [NBP2-87570]

Western Blot: Histone H1.2 Antibody [NBP2-87570] - WB Suggested Anti-HIST1H1C Antibody Titration: 0.2-1 ug/ml. Positive Control: 721_B cell lysateHIST1H1C is supported by BioGPS gene expression data to be expressed in 721_B
Immunohistochemistry-Paraffin: Histone H1.2 Antibody [NBP2-87570]

Immunohistochemistry-Paraffin: Histone H1.2 Antibody [NBP2-87570]

Immunohistochemistry-Paraffin: Histone H1.2 Antibody [NBP2-87570] - Rabbit Anti-HIST1H1C antibody. Formalin Fixed Paraffin Embedded Tissue: Human Testis. Primary antibody Concentration: 1:100. Secondary Antibody: Donkey anti-Rabbit-Cy3. Secondary Antibody Concentration: 1:200. Magnification: 20x.
Chromatin Immunoprecipitation: Histone H1.2 Antibody [NBP2-87570] - Chromatin Immunoprecipitation (ChIP) Using HIST1H1C antibody - middle region and HCT116 Cells
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Applications for Histone H1.2 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Histone H1.2

Histones are nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber as they play a critical role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. The Histone H1.2 protein is 213 amino acids long, 21 kDA and is encoded by the HIST1H1C gene. H1 proteins are essential in forming chromatin fiber and for the condensation of nucleosome chains into higher-order structured fibers. The HIST1H1C gene has been investigated in leukemia and parkinson's disease. It plays a role in apoptosis, PKA signaling, cell cycle chromosome condensation in prometaphase, and histone modification through interactions with various genes such as TONSL, NPM1, YWHAQ, EED, and ESR2.

Alternate Names

H1 histone family, member 2, H1.2, H1F2H1C, histone 1, H1c, histone cluster 1, H1c, histone H1.2, Histone H1d, MGC3992

Gene Symbol

H1-2

Additional Histone H1.2 Products

Product Documents for Histone H1.2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Histone H1.2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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