HLA DQB2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14984

Novus Biologicals, part of Bio-Techne
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NBP2-14984
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HLA DQB2 Antibodies »

Product Summary for HLA DQB2 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human HLA DQB2. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

27 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for HLA DQB2 Antibody

Western Blot: HLA DQB2 Antibody [NBP2-14984]

Western Blot: HLA DQB2 Antibody [NBP2-14984]

Western Blot: HLA DQB2 Antibody [NBP2-14984] - Sample (30 ug of whole cell lysate) A: K562 12% SDS PAGE diluted at 1:1000
Immunohistochemistry-Paraffin: HLA DQB2 Antibody [NBP2-14984]

Immunohistochemistry-Paraffin: HLA DQB2 Antibody [NBP2-14984]

Immunohistochemistry-Paraffin: HLA DQB2 Antibody [NBP2-14984] - Paraffin-embedded Colon ca, using antibody at 1:500 dilution.

Applications for HLA DQB2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: HLA DQB2

HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus. [provided by RefSeq]

Alternate Names

class II, DQ beta 1, DV19.1 (major histocompatibility complex, class II, DQ beta 2 (HLA-DXB)), HLA-DQB1, major histocompatibility complex, class II, DQ beta 2

Gene Symbol

HLA-DQB2

Additional HLA DQB2 Products

Product Documents for HLA DQB2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HLA DQB2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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