HLA DRA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00003122-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HLA DRA Antibodies »

Product Specifications

Immunogen

HLA-DRA (AAH32350, 1 a.a. - 254 a.a.) full-length human protein. MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIKGLRKSNAAERRGPL

Specificity

HLA-DRA - major histocompatibility complex, class II, DR alpha,

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for HLA DRA Antibody

Western Blot: HLA DRA Antibody [H00003122-B01P]

Western Blot: HLA DRA Antibody [H00003122-B01P]

Western Blot: HLA DRA Antibody [H00003122-B01P] - Analysis of HLA-DRA expression in human spleen.
Western Blot: HLA DRA Antibody [H00003122-B01P]

Western Blot: HLA DRA Antibody [H00003122-B01P]

Western Blot: HLA DRA Antibody [H00003122-B01P] - Analysis of HLA-DRA expression in human kidney.
Western Blot: HLA DRA Antibody [H00003122-B01P]

Western Blot: HLA DRA Antibody [H00003122-B01P]

Western Blot: HLA DRA Antibody [H00003122-B01P] - Analysis of HLA-DRA expression in transfected 293T cell line by HLA-DRA polyclonal antibody. Lane 1: HLA-DRA transfected lysate(28.05 KDa). Lane 2: Non-transfected lysate.

Applications for HLA DRA Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against transfected lysate and tissue lysate for WB. It has been used for ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: HLA DRA

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq]

Alternate Names

FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW

Entrez Gene IDs

3122 (Human)

Gene Symbol

HLA-DRA

UniProt

AAH32350 (Human)

Additional HLA DRA Products

Product Documents for HLA DRA Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HLA DRA Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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