HMBS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-30627

Novus Biologicals, part of Bio-Techne
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NBP3-30627
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Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all HMBS Antibodies »

Product Specifications

Immunogen

Between 311 and 361

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HMBS Antibody

HMBS Antibody

Immunoprecipitation:HMBS AntibodyNBP3-30627] -

Immunoprecipitation:HMBS AntibodyNBP3-30627] -Detection of human HMBS by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-HMBS antibody NBP3-30627 (lot NBP3-30627-1) used for IP at 6 µg/mg lysate. HMBS was also immunoprecipitated by rabbit anti-HMBS antibody. For blotting immunoprecipitated HMBS, NBP3-30627 was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

Applications for HMBS Antibody

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: HMBS

HMBS encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternate Names

hydroxymethylbilane synthasePre-uroporphyrinogen synthase, PBGDPBG-D, PORC, porphobilinogen deaminase, porphyria, acute; Chester type, UPSEC 2.5.1.61, uroporphyrinogen I synthase, uroporphyrinogen I synthetase

Gene Symbol

HMBS

Additional HMBS Products

Product Documents for HMBS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HMBS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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