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HMGCL Antibody (S08-7H5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19654

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-19654-50ul
NBP3-19654-100ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-7H5

Concentration

0.3 mg/ml

Product Summary for HMGCL Antibody (S08-7H5)

Immunogen

A synthetic peptide of human HMGCL (Uniprot # P35914)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

34 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for HMGCL Antibody (S08-7H5)

Western Blot: HMGCL Antibody (S08-7H5) [NBP3-19654]

Western Blot: HMGCL Antibody (S08-7H5) [NBP3-19654]

Western Blot: HMGCL Antibody (S08-7H5) [NBP3-19654] - Western blot detection of HMGCL in Hela cell lysates using NBP3-19654 (1:1000 diluted). Predicted band size: 34kDa. Observed band size: 34kDa.

Applications for HMGCL Antibody (S08-7H5)

Application
Recommended Usage

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HMGCL

The protein encoded by the HMGCL gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes thefinal step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associatedwith HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been foundfor this gene. (provided by RefSeq)

Alternate Names

3-hydroxy-3-methylglutaryl-CoA lyase, 3-hydroxymethyl-3-methylglutaryl-CoA lyase, EC 4.1.3.4, HLmitochondrial

Gene Symbol

HMGCL

Additional HMGCL Products

Product Documents for HMGCL Antibody (S08-7H5)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HMGCL Antibody (S08-7H5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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