HMGN2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12793

Novus Biologicals, part of Bio-Techne
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NBP3-12793-100ul
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Key Product Details

Species Reactivity

Mouse

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all HMGN2 Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Mouse HMGN2

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Scientific Data Images for HMGN2 Antibody

Immunohistochemistry-Paraffin: HMGN2 Antibody [NBP3-12793]

Immunohistochemistry-Paraffin: HMGN2 Antibody [NBP3-12793]

Immunohistochemistry-Paraffin: HMGN2 Antibody [NBP3-12793] - Staining of human HMGN2 in human colon with rabbit polyclonal antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: HMGN2 Antibody [NBP3-12793]

Immunohistochemistry-Paraffin: HMGN2 Antibody [NBP3-12793]

Immunohistochemistry-Paraffin: HMGN2 Antibody [NBP3-12793] - Staining of human HMGN2 in human thyroid with rabbit polyclonal antibody at 1:200 dilution.

Applications for HMGN2 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:100-1:500

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HMGN2

HMG17 (high mobility group transcription factor 17) is an 18 kD high mobility group chromosomal protein. This nuclear protein is common to all eukaryotes and is developmentally regulated. HMG17 binds DNA in a non-sequence specific manner and interacts with nucleosomes to modulate chromatin structure. HMG17 regulates the gene expression of p53, Hox transcription factors, and steroid hormone receptors (increases DNA binding affinity). Phosphorylation of HMG17 may interfere with nuclear localization and favor release from nuclei. HMG17 is upregulated by wild-type p53 and increases during embryogenesis and is downregulated during differentiation and development. This protein is modified by phosphorylation and acetylation. HMG17 interacts with nucleosomes and probably forms multi-unit complexes with unrelated proteins. The Poly6081 antibody recognizes human and mouse HMG17 and has been shown to be useful for Western blotting.

Alternate Names

High mobility group nucleosome-binding domain-containing protein 2, high-mobility group (nonhistone chromosomal) protein 17, high-mobility group nucleosomal binding domain 2, HMG17high mobility group protein N2, MGC5629, MGC88718, non-histone chromosomal protein HMG-17, nonhistone chromosomal protein HMG-17

Gene Symbol

HMGN2

Additional HMGN2 Products

Product Documents for HMGN2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HMGN2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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