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HMGN3/TRIP7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86904

Novus Biologicals, part of Bio-Techne
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NBP1-86904
NBP1-86904-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: KPEPKPRKTSAKKEPGAKISRGAKGKKEEKQEAGKEGTAPSENGETKAEEAQKTESVDNEGE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HMGN3/TRIP7 Antibody

Immunocytochemistry/ Immunofluorescence: HMGN3/TRIP7 Antibody [NBP1-86904]

Immunocytochemistry/ Immunofluorescence: HMGN3/TRIP7 Antibody [NBP1-86904]

Immunocytochemistry/Immunofluorescence: HMGN3/TRIP7 Antibody [NBP1-86904] - Staining of human cell line U-2 OS shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: HMGN3/TRIP7 Antibody [NBP1-86904]

Immunohistochemistry-Paraffin: HMGN3/TRIP7 Antibody [NBP1-86904]

Immunohistochemistry-Paraffin: HMGN3/TRIP7 Antibody [NBP1-86904] - Staining in human fallopian tube and pancreas tissues using anti-HMGN3 antibody. Corresponding HMGN3 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: HMGN3/TRIP7 Antibody [NBP1-86904]

Immunohistochemistry-Paraffin: HMGN3/TRIP7 Antibody [NBP1-86904]

Immunohistochemistry-Paraffin: HMGN3/TRIP7 Antibody [NBP1-86904] - Staining of human fallopian tube shows high expression.

Applications for HMGN3/TRIP7 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HMGN3/TRIP7

Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Two transcript variants encoding different isoforms have been found for this gene.

Alternate Names

DKFZp686E20226, high mobility group nucleosomal binding domain 3, high mobility group nucleosome-binding domain-containing protein 3, high-mobility group protein HMGN3, PNAS-25, thyroid hormone receptor interacting protein 7, thyroid hormone receptor interactor 7, Thyroid receptor-interacting protein 7, TR-interacting protein 7, TRIP-7, TRIP7FLJ42187

Gene Symbol

HMGN3

Additional HMGN3/TRIP7 Products

Product Documents for HMGN3/TRIP7 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HMGN3/TRIP7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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