hnRNP C1 + C2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-57153

Novus Biologicals, part of Bio-Techne
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NBP1-57153
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all hnRNP C1 + C2 Antibodies »

Product Summary for hnRNP C1 + C2 Antibody

Immunogen

Synthetic peptides corresponding to HNRNPC(heterogeneous nuclear ribonucleoprotein C (C1/C2)) The peptide sequence was selected from the middle region of HNRNPC. Peptide sequence ESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEEGEDDRDSAN. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for hnRNP C1 + C2 Antibody

Western Blot: hnRNP C1 + C2 Antibody [NBP1-57153]

Western Blot: hnRNP C1 + C2 Antibody [NBP1-57153]

Western Blot: hnRNP C1 + C2 Antibody [NBP1-57153] - HNRNPC antibody - middle region validated by WB using human microvascular endothelial cells (25ug) at 1:1,000.
Immunohistochemistry-Paraffin: hnRNP C1 + C2 Antibody [NBP1-57153]

Immunohistochemistry-Paraffin: hnRNP C1 + C2 Antibody [NBP1-57153]

Immunohistochemistry-Paraffin: hnRNP C1 + C2 Antibody [NBP1-57153] - Human Breast Tissue, antibody concentration 5ug/ml.
Western Blot: hnRNP C1 + C2 Antibody [NBP1-57153]

Western Blot: hnRNP C1 + C2 Antibody [NBP1-57153]

Western Blot: hnRNP C1 + C2 Antibody [NBP1-57153] - A549 cell lysate, Antibody Titration: 0.2-1 ug/ml

Applications for hnRNP C1 + C2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: hnRNP C1 + C2

This protein is associated with pre-mRNAs in the nucleus and appears to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein acts as a tetramer and is involved in the assembly of 40S hnRNP particles. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.

Alternate Names

C1, C2, heterogeneous nuclear ribonucleoprotein C (C1/C2), heterogeneous nuclear ribonucleoproteins C1/C2, HNRNP, hnRNP C1/C2, hnRNPC, HNRPC, MGC104306, MGC105117, MGC117353, MGC131677, nuclear ribonucleoprotein particle C1 protein, nuclear ribonucleoprotein particle C2 protein, SNRPC

Gene Symbol

HNRNPC

UniProt

P07910 (Human)

Additional hnRNP C1 + C2 Products

Product Documents for hnRNP C1 + C2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for hnRNP C1 + C2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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