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hnRNP M Antibody (S06-3B1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15042

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-15042-100ul
NBP3-15042-25ul

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S06-3B1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

A synthetic peptide of human hnRNP M (Uniprot#: P52272)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

78 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for hnRNP M Antibody (S06-3B1)

Western Blot: hnRNP M Antibody (S06-3B1) [NBP3-15042]

Western Blot: hnRNP M Antibody (S06-3B1) [NBP3-15042]

Western Blot: hnRNP M Antibody (S06-3B1) [NBP3-15042] - Western blot detection of hnRNP M in K562, C6, 3T3, Hela cell lysates using hnRNP M Rabbit mAb (1:1000 diluted). Predicted band size: 78kDa. Observed band size: 78kDa.
Immunohistochemistry-Paraffin: hnRNP M Antibody (S06-3B1) [NBP3-15042]

Immunohistochemistry-Paraffin: hnRNP M Antibody (S06-3B1) [NBP3-15042]

Immunohistochemistry-Paraffin: hnRNP M Antibody (S06-3B1) [NBP3-15042] - Immunohistochemistry of hnRNP M in paraffin-embedded Human tonsil using hnRNP M Rabbit mAb at dilution 1/50

Applications for hnRNP M Antibody (S06-3B1)

Application
Recommended Usage

Immunohistochemistry

1/20

Western Blot

1/1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: hnRNP M

Proteins that directly bind to nascent RNA polymerase II transcripts--the heterogenous nuclear ribonucleoproteins (hnRNPs)--play an important role in both transcript-specific packaging and alternative splicing of pre-mRNAs. A group of abundant hnRNPs, the M1-M4 proteins, appear as a cluster of four proteins. The M proteins are pre-mRNA binding proteins in vivo, and they bind avidly to poly (G) and poly (U) RNA homopolymers in vitro. M proteins are members of the ribonucleoprotein consensus sequence family of RNA-binding proteins with greatest similarity to a hypothetical RNA-binding protein from Saccharomyces cerevisiae. The M proteins also possess an unusual hexapeptide-repeat region rich in methionine and arginine residues (MR repeat motif) that resembles a repeat in the 64kDa subunit of cleavage stimulation factor, which is involved in end maturation of pre-mRNAs. Proteins immunologically related to M exist in divergent eukaryotes ranging from human to yeast.

Alternate Names

DKFZp547H118, heterogeneous nuclear ribonucleoprotein M, hnRNP M, HNRNPM4, HNRPM4heterogenous nuclear ribonucleoprotein M, HNRPMheterogenous nuclear ribonucleoprotein M4, HTGR1, M4 protein, N-acetylglucosamine receptor 1, NAGR1hnRNA-binding protein M4

Gene Symbol

HNRNPM

Additional hnRNP M Products

Product Documents for hnRNP M Antibody (S06-3B1)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for hnRNP M Antibody (S06-3B1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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