HNRPGT Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-57164

Novus Biologicals, part of Bio-Techne
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NBP1-57164
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all HNRPGT Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to RBMXL2(RNA binding motif protein, X-linked-like 2) or HNRPGT The peptide sequence was selected from the middle region of HNRPGT. Peptide sequence SSRDGYSSRDYREPRGFAPSPGEYTHRDYGHSSVRDDCPLRGYSDRDGYG. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for HNRPGT Antibody

Western Blot: HNRPGT Antibody [NBP1-57164]

Western Blot: HNRPGT Antibody [NBP1-57164]

Western Blot: HNRPGT Antibody [NBP1-57164] - 293T cells lysate, concentration 0.2-1 ug/ml.

Applications for HNRPGT Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HNRPGT

The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2215 AC100875.3 67063-69277 c

Alternate Names

hnRNP G-T, HNRNPG-T, HNRNPGTRNA-binding motif protein, X-linked-like-2, HNRPGTheterogeneous nuclear ribonucleoprotein G T, RNA binding motif protein, X-linked-like 2, testes specific heterogenous nuclear ribonucleoprotein G T, testes-specific heterogenous nuclear ribonucleoprotein G-T, Testis-specific heterogeneous nuclear ribonucleoprotein G-T

Gene Symbol

RBMXL2

UniProt

O75526 (Human)

Additional HNRPGT Products

Product Documents for HNRPGT Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for HNRPGT Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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