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HOXD10 Antibody (OTI1D11)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-45744

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # OTI1D11

Concentration

1 mg/ml

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 80-340 of human HOXD10 (NP_002139) produced in E.coli.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

38.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for HOXD10 Antibody (OTI1D11)

Western Blot: HOXD10 Antibody (OTI1D11) [NBP2-45744]

Western Blot: HOXD10 Antibody (OTI1D11) [NBP2-45744]

Western Blot: HOXD10 Antibody (1D11) [NBP2-45744] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HOXD10.
Immunohistochemistry: HOXD10 Antibody (OTI1D11) [NBP2-45744]

Immunohistochemistry: HOXD10 Antibody (OTI1D11) [NBP2-45744]

Immunohistochemistry: HOXD10 Antibody (1D11) [NBP2-45744] - Analysis of Carcinoma of Human bladder tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemistry: HOXD10 Antibody (OTI1D11) [NBP2-45744]

Immunohistochemistry: HOXD10 Antibody (OTI1D11) [NBP2-45744]

Immunohistochemistry: HOXD10 Antibody (1D11) [NBP2-45744] - Analysis of Carcinoma of Human pancreas tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Applications for HOXD10 Antibody (OTI1D11)

Application
Recommended Usage

Immunohistochemistry

1:150

Western Blot

1:500

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: HOXD10

HOXD10 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as rocker-bottom foot deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

Long Name

Homeobox D10

Alternate Names

HOX4, HOX4D, HOX4E

Gene Symbol

HOXD10

Additional HOXD10 Products

Product Documents for HOXD10 Antibody (OTI1D11)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HOXD10 Antibody (OTI1D11)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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