HRD1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-06671

Novus Biologicals, part of Bio-Techne
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NBP3-06671
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bat (100%), Bovine (100%), Canine (100%), Equine (100%), Hamster (100%), Monkey (100%), Mouse (100%), Opossum (100%), Rabbit (100%), Rat (100%), Xenopus (100%), Zebrafish (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Format

BSA Free

Concentration

1 mg/ml

View all HRD1 Antibodies »

Product Specifications

Immunogen

Synthetic 18 aa peptide from internal region of human HRD1.

Epitope

Internal region

Reactivity Notes

Gorilla (100%), Gibbon (100%), Marmoset (100%)

Specificity

Human HRD1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for HRD1 Antibody - BSA Free

Immunohistochemistry-Paraffin: HRD1 Antibody - BSA Free [NBP3-06671]

Immunohistochemistry-Paraffin: HRD1 Antibody - BSA Free [NBP3-06671]

Immunohistochemistry-Paraffin: HRD1 Antibody [NBP3-06671] - HRD1 Antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Applications for HRD1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

5-10 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: HRD1

HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. It has been reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its anti-apoptotic effects. HRD1 contains one ring-type zinc finger.

Alternate Names

E3 ubiquitin-protein ligase synoviolin, EC 6.3.2, HRD1EC 6.3.2.-, KIAA1810Synovial apoptosis inhibitor 1, MGC40372, synovial apoptosis inhibitor 1, synoviolin

Gene Symbol

SYVN1

Additional HRD1 Products

Product Documents for HRD1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HRD1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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