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HSD17B12 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81567

Novus Biologicals, part of Bio-Techne
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NBP1-81567
NBP1-81567-25ul

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: WGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLD

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (83%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HSD17B12 Antibody

Immunohistochemistry-Paraffin: HSD17B12 Antibody [NBP1-81567]

Immunohistochemistry-Paraffin: HSD17B12 Antibody [NBP1-81567]

Immunohistochemistry-Paraffin: HSD17B12 Antibody [NBP1-81567] - Staining of human colon shows moderate to strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: HSD17B12 Antibody [NBP1-81567]

Immunohistochemistry-Paraffin: HSD17B12 Antibody [NBP1-81567]

Immunohistochemistry-Paraffin: HSD17B12 Antibody [NBP1-81567] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: HSD17B12 Antibody [NBP1-81567]

Immunohistochemistry-Paraffin: HSD17B12 Antibody [NBP1-81567]

Immunohistochemistry-Paraffin: HSD17B12 Antibody [NBP1-81567] - Staining of human testis shows strong cytoplasmic positivity in Leydig cells.

Applications for HSD17B12 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HSD17B12

The enzyme 17-beta hydroxysteroid dehydrogenase-12 (HSD17B12) uses NADPH to reduce 3-ketoacyl-CoA to 3-hydroxyacyl-CoA during the second step of fatty acid elongation.[supplied by OMIM]

Alternate Names

17-beta-HSD 12, 17-beta-hydroxysteroid dehydrogenase 12, EC 1.1.1.62,3-ketoacyl-CoA reductase, EC 1.3.1.-, hydroxysteroid (17-beta) dehydrogenase 12,17beta-HSD type 12, KARestradiol 17-beta-dehydrogenase 12, SDR12C1, short chain dehydrogenase/reductase family 12C, member 1, steroid dehydrogenase homolog

Gene Symbol

HSD17B12

Additional HSD17B12 Products

Product Documents for HSD17B12 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HSD17B12 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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