HSD17B6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-32431

Novus Biologicals, part of Bio-Techne
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NBP2-32431
NBP2-32431-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HSD17B6 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: VEPGYFRTGMTNMTQSLERMKQSWKEAPKHIKETYGQQYFDALYNIMKEGLL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HSD17B6 Antibody

Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP2-32431]

Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP2-32431]

Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP2-32431] - Staining in human liver and pancreas tissues using anti-HSD17B6 antibody. Corresponding HSD17B6 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP2-32431]

Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP2-32431]

Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP2-32431] - Staining of human testis shows strong cytoplasmic positivity in Leydig cells.
Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP2-32431]

Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP2-32431]

Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP2-32431] - Staining of human liver shows high expression.
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Applications for HSD17B6 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HSD17B6

HSD17B6 is encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist. [provided by RefSeq]

Alternate Names

17-beta-HSD 6, 17-beta-HSD6, 17-beta-hydroxysteroid dehydrogenase type 6, 3(alpha->beta)-hydroxysteroid epimerase, 3-alpha->beta-HSE, EC 1.1.1, EC 1.1.1.105, EC 1.1.1.62, EC 1.1.1.63, HSE3-hydroxysteroid epimerase, hydroxysteroid (17-beta) dehydrogenase 6, hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse), NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase, Oxidative 3-alpha hydroxysteroid dehydrogenase, oxidative 3-alpha-hydroxysteroid-dehydrogenase, oxidoreductase, retinol dehydrogenase, RODH3(alpha->beta)-hydroxysteroid epimerasel, SDR9C6, short chain dehydrogenase/reductase family 9C, member 6,3-alpha->beta-hydroxysteroid epimerase

Gene Symbol

HSD17B6

Additional HSD17B6 Products

Product Documents for HSD17B6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HSD17B6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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