HTRA1/PRSS11 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81654

Novus Biologicals, part of Bio-Techne
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NBP1-81654
NBP1-81654-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Simple Western

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HTRA1/PRSS11 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GSDANTYANLCQLRAASRRSERLHRPPVIVLQRGACGQGQEDPNSLRHKYNFIA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HTRA1/PRSS11 Antibody

Immunocytochemistry/ Immunofluorescence: HTRA1/PRSS11 Antibody [NBP1-81654]

Immunocytochemistry/ Immunofluorescence: HTRA1/PRSS11 Antibody [NBP1-81654]

Immunocytochemistry/Immunofluorescence: HTRA1/PRSS11 Antibody [NBP1-81654] - Staining of human cell line LHCN-M2 shows localization to plasma membrane. Antibody staining is shown in green.

Applications for HTRA1/PRSS11 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100. Simple Western reported by internal validation: Tested in human blood vessel lysates; separated by size; antibody dilution of 1:50.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HTRA1/PRSS11

htrA1 encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Long Name

High Temperature Requirement Protein-1

Alternate Names

IGFBP5-protease, PRSS11

Gene Symbol

HTRA1

Additional HTRA1/PRSS11 Products

Product Documents for HTRA1/PRSS11 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HTRA1/PRSS11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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