HuC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-29864

Novus Biologicals, part of Bio-Techne
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NBP2-29864
NBP2-29864-0.025mg
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all HuC Antibodies »

Product Specifications

Immunogen

Synthetic peptide, amino acids 20-46 of HuC.

Specificity

Recognizes HuC. The molecular weight of the protein is 38,862 Daltons.

Marker

Neuronal & Glial Markers

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

38.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Relevant Entrez Gene Numbers: NM_001420.3;NM_032281.2

Applications for HuC Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:200-1:1000

Western Blot

1:200-1:1000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50% saturated ammonium sulfate and PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: HuC

HuC is a member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

DKFZp547J036, ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C), ELAV-like protein 3, Hu antigen C, Hu-antigen C, HuC, HUCL, HUCParaneoplastic cerebellar degeneration-associated antigen, MGC20653, PLE21Paraneoplastic limbic encephalitis antigen 21

Gene Symbol

ELAVL3

UniProt

Q14576 (Human)

Additional HuC Products

Product Documents for HuC Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HuC Antibody

Relevant Entrez Gene Numbers: NM_001420.3;NM_032281.2

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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