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Human Activin C betaC subunit Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB1629

R&D Systems, part of Bio-Techne
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MAB1629
MAB1629-SP

Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 203522

Product Specifications

Immunogen

E. coli-derived recombinant human Activin C betaC subunit
Gly237-Ser352
Accession # P55103

Specificity

Detects human Activin C betaC subunit in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Activin A, B, AB, rhInhibin A, B, or recombinant mouse Activin C is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Human Activin C betaC subunit Antibody

Human Activin C ELISA Standard Curve.

Recombinant Human Activin C protein was serially diluted 2-fold and captured by Mouse Anti-Human Activin C betaC subunit Monoclonal Antibody (Catalog # MAB1629) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human Activin C betaC subunit Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1629) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998) followed by Substrate Solution (Catalog # DY999) and stopping the enzymatic reaction with Stop Solution (Catalog # DY994).

Applications for Human Activin C betaC subunit Antibody

Application
Recommended Usage

ELISA

This antibody functions as an ELISA capture antibody when paired with Goat Anti-Human Activin C betaC subunit Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1629).

This product is intended for assay development on various assay platforms requiring antibody pairs.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Activin C

Activins belong to the TGF-beta superfamily. They are homo- or heterodimers of Activin beta subunits. At least four mammalian beta subunits, A, B, C, and E, have been described. The betac subunit homodimerizes to form Activin CC. A naturally occuring Activin AC heterodimer has also been reported (1).

References

  1. Mellor, S. et al. (2003) Endocrinology 144:4410.

Alternate Names

INHBC

Entrez Gene IDs

3626 (Human); 16325 (Mouse)

Gene Symbol

INHBC

UniProt

Additional Activin C Products

Product Documents for Human Activin C betaC subunit Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Activin C betaC subunit Antibody

For research use only

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