Human AGTR-2 PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB3659P

R&D Systems, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 364805

View all AGTR-2 Antibodies »

Product Specifications

Immunogen

HEK293 human embryonic kidney cell line transfected with human AGTR-2
Met1-Ser363
Accession # P50052

Specificity

Detects human AGTR‑2. Stains human AGTR-2-transfected cells but not irrelevant transfectants.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Human AGTR-2 PE-conjugated Antibody

Detection of AGTR-2 antibody in NS0 Mouse Cell Line Transfected with AGTR-2 antibody by Flow Cytometry.

Detection of AGTR-2 in NS0 Mouse Cell Line Transfected with AGTR-2 by Flow Cytometry.

NS0 mouse myeloma cell line transfected with AGTR-2 was stained with Mouse Anti-Human AGTR-2 PE-conjugated Monoclonal Antibody (Catalog # FAB3659P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human AGTR-2 PE-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: NS0 mouse myeloma cell line transfected with AGTR-2

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: AGTR-2

AGTR-2, also known as AT2, is a 7-transmembrane protein that belongs to family 1 of G protein-coupled receptors. Both AGTR-2 and AGTR-1 bind Angiotensin II and function in the control of hemodynamics. In contrast to AGTR-1, which promotes vasoconstriction and cell proliferation, AGTR-2 inhibits growth and promotes apoptosis. In addition, Angiotensin II-induced AGTR-2 signaling induces the release of nitric oxide in the heart, kidney, and brain and participates in tissue morphogenesis and repair. Human AGTR-2 shares 92% amino acid sequence identity with mouse and rat AGTR-2.

Long Name

Angiostensin II Type 2 Receptor

Alternate Names

AGTR2, AT2, AT2R, MRX88

Entrez Gene IDs

186 (Human); 11609 (Mouse); 24182 (Rat)

Gene Symbol

AGTR2

UniProt

P50052

Additional AGTR-2 Products

Product Documents for Human AGTR-2 PE-conjugated Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human AGTR-2 PE-conjugated Antibody

For research use only

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