Human CAR/NR1I3 Antibody

R&D Systems, part of Bio-Techne | Catalog # PP-N4111-00

R&D Systems, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human, Mouse, Primate - Chlorocebus aethiops (African Green Monkey), Rabbit, Transgenic Mouse

Applications

Validated:

Immunohistochemistry, Immunoprecipitation, Western Blot

Cited:

Chromatin Immunoprecipitation (ChIP), Immunocytochemistry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # N4111

View all CAR/NR1I3 Antibodies »

Product Specifications

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human CAR/NR1I3 Antibody

Application
Recommended Usage

Immunohistochemistry

Immunoprecipitation

Western Blot

Formulation, Preparation, and Storage

Formulation

A liquid formulation in physiologic saline with 0.1% NaN3.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: CAR/NR1I3

CAR, (MB67; NR1I3) is a 40 kDa member of the NR1 subfamily of the nuclear hormone receptor family. CAR is predominantly expressed in the liver and forms a heterodimer with RXR. The CAR/RXR heterodimer activates retinoic acid, xenobiotic and phenobarbital response elements. There are two isoforms of the CAR nuclear hormone receptor. Each contains a DNA-binding hinge and dimerization domain. One is full-length at 352 amino acids while the other shows a 4 amino acid truncation at the extreme C-terminus.

Long Name

Constitutive Androstane Receptor

Alternate Names

MB67, NR1I3

Entrez Gene IDs

9970 (Human)

Gene Symbol

NR1I3

Additional CAR/NR1I3 Products

Product Documents for Human CAR/NR1I3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human CAR/NR1I3 Antibody

For research use only

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