Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Monoclonal Mouse IgM Clone # 674144

View all CCR11 Antibodies »

Product Specifications

Immunogen

NS0 mouse myeloma cell line transfected with human CCR11
Accession # Q9NPB9

Specificity

Detects human CCR11 in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgM

Scientific Data Images for Human CCR11 PE-conjugated Antibody

Detection of CCR11 antibody in HEK293 Human Cell Line Transfected with Human CCR11 and eGFP antibody by Flow Cytometry.

Detection of CCR11 in HEK293 Human Cell Line Transfected with Human CCR11 and eGFP by Flow Cytometry.

HEK293 human embryonic kidney cell line transfected with either (A) human CCR11 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human CCR11 PE-conjugated Monoclonal Antibody (Catalog # FAB6899P). Quadrant markers were set based on control antibody staining (Catalog # IC105P). View our protocol for Staining Membrane-associated Proteins.

Applications for Human CCR11 PE-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: HEK293 Human Cell Line Transfected with Human CCR11 and eGFP

Formulation, Preparation, and Storage

Purification

IgM-specific Affinity-purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CCR11

CCR11, also known as CCRL1 and CCX-CKR, is a 45 kDa 7-transmembrane segment protein that is widely expressed on stromal cells. It is a silent receptor that does not induce intracellular calcium signaling, but instead serves as a chemokine scavenger receptor. CCR11 regulates dendritic cell and thymic precursor migration by mediating the clearance of the homeostatic chemokines CCL19, 21, and 25. It is upregulated on some breast cancer cells and on bronchial epithelial cells in pulmonary sarcoidosis. Human CCR11 shares 85% amino acid sequence identity with mouse and rat CCR11.

Alternate Names

ACKR4, CC-CKR-11, CCRL1, CCX-CKR, PPR1, VSHK1

Entrez Gene IDs

51554 (Human); 252837 (Mouse); 685243 (Rat)

Gene Symbol

ACKR4

UniProt

Q9NPB9

Additional CCR11 Products

Product Documents for Human CCR11 PE-conjugated Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human CCR11 PE-conjugated Antibody

For research use only

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