Human CD39L2/ENTPD6 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB4399
Key Product Details
Species Reactivity
Human
Applications
Immunoprecipitation, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2B Clone # 494402
Product Specifications
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human CD39L2/ENTPD6
Lys61-Ser484
Accession # O75354
Lys61-Ser484
Accession # O75354
Specificity
Detects human CD39L2/ENTPD6 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) CD39, rhCD39L3, or recombinant mouse CD39 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for Human CD39L2/ENTPD6 Antibody
Application
Recommended Usage
Immunoprecipitation
25 µg/mL
Sample: Conditioned cell culture medium spiked with Recombinant Human CD39L2/ENTPD6 (Catalog # 4399-EN), see our available Western blot detection antibodies
Sample: Conditioned cell culture medium spiked with Recombinant Human CD39L2/ENTPD6 (Catalog # 4399-EN), see our available Western blot detection antibodies
Western Blot
1 µg/mL
Sample: Recombinant Human CD39L2/ENTPD6 (Catalog # 4399-EN)
Sample: Recombinant Human CD39L2/ENTPD6 (Catalog # 4399-EN)
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CD39L2/ENTPD6
ENTPD6 (ectonucleoside triphosphate diphosphohydrolase-6), also known as CD39L2, is a secreted nucleoside phosphohydrolase, which catalyzes the hydrolysis of extracellular nucleotides, such as nucleoside 5'-diphosphates and nucleoside 5'-triphosphates (1). Human ENTPD6 displays a preference for the nucleoside-5’-diphosphates GDP and IDP over CDP and UDP (2). It has a broad tissue distribution, with major expression in the heart. The amino acid sequence of human CD39L2 shares 99%, 88% and 87% identity with that of chimpanzee, mouse and dog, respectively.
References
- Chadwick, B.P. and A.M. Frischauf (1998) Genomics. 50:357.
- Hicks-Berger, C.A. et al. (2000) J. Biol. Chem. 275:34041.
Long Name
Ecto-Nucleoside Triphosphate Diphosphohydrolase 6
Alternate Names
CD39L2, ENTPD6, NTPD3, NTPDase 6
Gene Symbol
ENTPD6
UniProt
Additional CD39L2/ENTPD6 Products
Product Documents for Human CD39L2/ENTPD6 Antibody
Product Specific Notices for Human CD39L2/ENTPD6 Antibody
For research use only
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