Human CILP-1 N-Terminal Fragment Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # BAF5504
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Biotin
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CILP‑1 N-Terminal Fragment
Arg22-Arg720
Accession # NP_003604
Arg22-Arg720
Accession # NP_003604
Specificity
Detects human CILP‑1 N-Terminal Fragment in Western blots. In Western blots, less than 1% cross‑reactivity with recombinant human CILP‑1 C‑terminal peptide is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Human CILP-1 N-Terminal Fragment Biotinylated Antibody
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Human CILP-1 N-Terminal Fragment
Sample: Recombinant Human CILP-1 N-Terminal Fragment
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CILP-1
The CILP-1 (cartilage intermediate-layer protein 1) gene product is a 132 kDa (predicted) monomeric glycoprotein that is found in both hyaline and fibrocartilage. It is a precursor for two secreted, proteolytically generated products, a 90 kDa N-terminal CILP-1, and a 62 kDa C-terminal NTPPHase-homolog. The N-terminus is suggested to serve as both a matrix structural protein, and an IGF-I/TGF-beta 1 suppressor sequestration molecule. Human CILP-1 spans aa 22‑720 of the CILP-1 precursor. It contains one TSP-1 domain (aa 149‑201), a C2‑type Ig-like region (aa 309‑395) and six potential N-glycosylation sites. Over aa 1‑720 of the CILP-1 precursor, human CILP-1 shares 89% aa identity with mouse CILP‑1, and 42% aa identity with human CILP-2.
Long Name
Cartilage Intermediate Layer Protein 1
Alternate Names
CILP, CILP1
Gene Symbol
CILP
UniProt
Additional CILP-1 Products
Product Documents for Human CILP-1 N-Terminal Fragment Biotinylated Antibody
Product Specific Notices for Human CILP-1 N-Terminal Fragment Biotinylated Antibody
For research use only
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