Human CRTH-2 PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB33381P

R&D Systems, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # 301109

View all CRTH-2 Antibodies »

Product Specifications

Immunogen

NS0 mouse myeloma cell line transfected with human CRTH-2
Met1-Ser395
Accession # Q9Y5Y4

Specificity

Detects human CRTH‑2 in Cell-Based ELISA.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for Human CRTH-2 PE-conjugated Antibody

Detection of CRTH-2 antibody in Human Blood Lymphocytes antibody by Flow Cytometry.

Detection of CRTH‑2 in Human Blood Lymphocytes by Flow Cytometry.

Human peripheral blood lymphocytes were stained with Mouse Anti-Human IL-3 Ra/CD123 PerCP-conjugated Monoclonal Antibody (Catalog # FAB301C) and either (A) Mouse Anti-Human CRTH-2 PE-conjugated Monoclonal Antibody (Catalog # FAB33381P) or (B) Mouse IgG2APhycoerythrin Isotype Control (Catalog # IC003P). View our protocol for Staining Membrane-associated Proteins.

Applications for Human CRTH-2 PE-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Human peripheral blood lymphocytes

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CRTH-2

CRTH-2, also known as GPR44, is a 7TM G protein-coupled receptor that is expressed by activated Th2 cells and eosinophils. CRTH-2 binds Prostaglandin D2 and induces chemotaxis of these cells in allergic and inflammatory immune responses. Human and mouse CRTH-2 share 78% amino acid sequence identity.

Long Name

Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells

Alternate Names

CD294, CRTH2, GPR44, PGD2R, PTGDR2

Entrez Gene IDs

11251 (Human); 14764 (Mouse); 309212 (Rat)

Gene Symbol

PTGDR2

UniProt

Q9Y5Y4

Additional CRTH-2 Products

Product Documents for Human CRTH-2 PE-conjugated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human CRTH-2 PE-conjugated Antibody

For research use only

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