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Human DCIR/CLEC4A Biotinylated Antibody

R&D Systems, part of Bio-Techne | Catalog # BAF1748

R&D Systems, part of Bio-Techne
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BAF1748

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Western Blot

Label

Biotin

Antibody Source

Polyclonal Goat IgG

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human DCIR/CLEC4A isoform 1
Gln70-Leu237
Accession # Q9UMR7

Specificity

Detects human DCIR/CLEC4A in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human DCIR/CLEC4A Biotinylated Antibody

Application
Recommended Usage

Flow Cytometry

2.5 µg/106 cells
Sample: Human whole blood granulocytes

Western Blot

0.1 µg/mL
Sample: Recombinant Human DCIR/CLEC4A
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: DCIR/CLEC4A

DCIR, also known as Lectin-like Immunoreceptor (LLIR), is a type II membrane protein belonging to the C-type lectin superfamily (CLECSF) and is designated CLEC4A. Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. Besides DC, DCIR is expressed on B cells, monocytes/macrophages and granulocytes.

Long Name

Dendritic Cell Immunoreceptor

Alternate Names

CD367, CLEC4A, CLECSF6, DDB27, LLIR

Entrez Gene IDs

50856 (Human); 26888 (Mouse)

Gene Symbol

CLEC4A

UniProt

Additional DCIR/CLEC4A Products

Product Documents for Human DCIR/CLEC4A Biotinylated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human DCIR/CLEC4A Biotinylated Antibody

For research use only

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