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Human FPRL1/FPR2 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB3479

R&D Systems, part of Bio-Techne
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MAB3479
MAB3479-SP

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

CyTOF-ready, Flow Cytometry

Cited:

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 304405

Product Specifications

Immunogen

NS0 mouse myeloma cell line transfected with human FPRL1
Met1-Met351
Accession # P25090

Specificity

Stains FPRL1 transfectants but not irrelevant transfectants. It also stains monocytes and granulocytes.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Human FPRL1/FPR2 Antibody

Detection of FPRL1/FPR2 antibody in Human Blood Monocytes antibody by Flow Cytometry.

Detection of FPRL1/FPR2 in Human Blood Monocytes by Flow Cytometry.

Human peripheral blood monocytes were stained with Mouse Anti-Human FPRL1/ FPR2 Monoclonal Antibody (Catalog # MAB3479, filled histogram) or isotype control antibody (Catalog # MAB004, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B). View our protocol for Staining Membrane-associated Proteins.

Applications for Human FPRL1/FPR2 Antibody

Application
Recommended Usage

CyTOF-ready

Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Flow Cytometry

0.25 µg/106 cells
Sample: Human peripheral blood monocytes

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: FPRL1/FPR2

FPRL1 is a 7TM protein expressed on mononuclear phagocytes and microglial cells. It interacts with formyl peptides to attract phagocytes to sites of infection and promote inflammatory reactions. FPRL1 also interacts with amyloid beta peptides and has been implicated in phagocyte attraction to sites of amyloid plaques in Alzheimer’s disease.

Long Name

Formyl Peptide Receptor-like 1

Alternate Names

ALXR, FMLP-R-I, FPR2, HM63, LXA4 Receptor, RFP

Entrez Gene IDs

2358 (Human); 14289 (Mouse)

Gene Symbol

FPR2

UniProt

Additional FPRL1/FPR2 Products

Product Documents for Human FPRL1/FPR2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human FPRL1/FPR2 Antibody

For research use only

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