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Human FPRL2/FPR3 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB3896

R&D Systems, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

CyTOF-ready, Flow Cytometry

Cited:

Flow Cytometry, Immunocytochemistry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 374822

Product Specifications

Immunogen

HEK293 human embryonic kidney cell line transfected with human FPRL2
Met1-Met352
Accession # P25089

Specificity

Detects human FPRL2. Stains human FPRL2 transfectants but not irrelevant transfectants.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human FPRL2/FPR3 Antibody

Application
Recommended Usage

CyTOF-ready

Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Flow Cytometry

0.25 µg/106 cells
Sample: NS0 mouse myeloma cell line transfected with human FPRL2

Reviewed Applications

Read 1 review rated 3 using MAB3896 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
Size / Price
Qty
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: FPRL2/FPR3

FPRL2, also known as FMLP receptor-like 2, is a 40 kDa 7TM protein that is expressed on monocytes and dendritic cells. It interacts with formyl and acetyl peptides to attract these cells to sites of infection. FPRL2 signaling also inhibits DC maturation. Human FPRL2 shares 63% and 62% amino acid sequence identity with mouse and rat FPRL2, respectively.

Long Name

Formyl Peptide Receptor-like 2

Alternate Names

FMLPY, FPR3, FPRH1, FPRH2, RMLP-R-I

Entrez Gene IDs

2359 (Human); 14294 (Mouse)

Gene Symbol

FPR3

UniProt

Additional FPRL2/FPR3 Products

Product Documents for Human FPRL2/FPR3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human FPRL2/FPR3 Antibody

For research use only

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