Human GPR107 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB10926
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # 1040717
Product Specifications
Immunogen
Human GPR107 synthetic peptide
Accession # Q5VW38
Accession # Q5VW38
Specificity
Detects human GPR107 in direct ELISAs.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Scientific Data Images for Human GPR107 Antibody
Detection of Human GPR107 by Western Blot.
Western blot shows lysates of non-boiled AGS human gastric adenocarcinoma cell line, KATO-III human gastric carcinoma cell line, and PANC-1 human pancreatic carcinoma cell line. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human GPR107 Monoclonal Antibody (Catalog # MAB10926) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (HAF018). A specific band was detected for GPR107 at approximately 80 kDa (as indicated). This experiment was conducted under reducing conditions and using Western Blot Buffer Group 1.Applications for Human GPR107 Antibody
Application
Recommended Usage
Western Blot
2 µg/mL
Sample: AGS human gastric adenocarcinoma cell line, KATO‑III human gastric carcinoma cell line, and PANC‑1 human pancreatic carcinoma cell line
Sample: AGS human gastric adenocarcinoma cell line, KATO‑III human gastric carcinoma cell line, and PANC‑1 human pancreatic carcinoma cell line
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: GPR107
Human GPR107 is an ‘orphan' 7-transmembrane receptor from the G protein-coupled receptor (GPCR) family of proteins.
GPR107 has been proposed to act as a receptor for Neuronostatin, a peptide derived from the somatostatin/SST precursor. Neuronostatin acts via GPR107 to increase cAMP-independent PKA phosphorylation and proglucagon mRNA accumulation in pancreatic alpha-cells.
Long Name
G Protein-coupled Receptor 107
Alternate Names
BA138E2.2, KIAA1624, LUSTR1
Gene Symbol
GPR107
UniProt
Additional GPR107 Products
Product Documents for Human GPR107 Antibody
Product Specific Notices for Human GPR107 Antibody
For research use only
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