Human ICAM-2/CD102 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB244
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Western Blot
Cited:
Flow Cytometry, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # 86911
Product Specifications
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human ICAM‑2/CD102
Lys25-Gln223 (predicted)
Accession # CAA33630
Lys25-Gln223 (predicted)
Accession # CAA33630
Specificity
Detects human ICAM‑2/CD102 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) CEACAM-1, recombinant mouse (rm) DCC, rhICAM-1, rmICAM-2, rhICAM-3, rmICAM-5, rmMAdCAM-1, rhCD31, or rmVCAM-1 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for Human ICAM-2/CD102 Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Human ICAM-2/CD102 Fc Chimera (Catalog # 803-I2)
Sample: Recombinant Human ICAM-2/CD102 Fc Chimera (Catalog # 803-I2)
Formulation, Preparation, and Storage
Purification
Protein A or G purified from ascites
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: ICAM-2/CD102
Intercellular Adhesion Molecule-2 (ICAM-2, CD102), a member of the immunoglobulin superfamily, binds the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). ICAM-2 is constitutively expressed at high levels on vascular endothelial cells and lymphohematopoietic cells. ICAM-2 mediated adhesion has been shown to provide a co-stimulatory signal for T cell aggregation, NK cytotoxicity and NK cell migration.
References
- Somersalo, K. et al. (1995) J. Biol. Chem. 270:8629.
- Hayflick, J. et al. (1998) Immunologic Res. 17:313.
Long Name
Intercellular Adhesion Molecule 2
Alternate Names
CD102, ICAM2
Gene Symbol
ICAM2
UniProt
Additional ICAM-2/CD102 Products
Product Documents for Human ICAM-2/CD102 Antibody
Product Specific Notices for Human ICAM-2/CD102 Antibody
For research use only
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