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Human IGFBP-rP10 Biotinylated Antibody

R&D Systems, part of Bio-Techne | Catalog # BAF5137

R&D Systems, part of Bio-Techne
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BAF5137

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Sheep IgG

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human IGFBP‑rP10 isoform 1
Arg31-Tyr304
Accession # Q96I82

Specificity

Detects human IGFBP-rP10 in Western blots. In Western blots, approximately 10% cross‑reactivity with recombinant mouse IGFBP-rP10 is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Human IGFBP-rP10 Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant human IGFBP-rP10

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IGFBP-rP10

IGFBP-rP10 (IGF binding protein-related protein 10; also Kazal-type serine protease inhibitor domain-contain protein 1 and BONO1) is a 37 kDa (predicted), secreted member of the IGFBP superfamily. It is expressed by osteoblasts and odontoblasts, is associated with regions of mineralization, and stimulates the proliferation of osteoblasts in vitro. Mature human IGFBP-rP10 is 274 amino acids (aa) in length. It contains an IGF binding domain (aa 49‑124), a follistatin-like serine protease inhibitor region (aa 125‑168) and a C2-type Ig‑like domain (aa 172‑269). There is one splice variant that shows a 70 aa substitution for aa 184‑304. Mature human IGFBP‑rP10 is 87% aa identical to mouse IGFBP-rP10.

Long Name

Insulin-like Growth Factor Binding Protein Related Protein-10

Alternate Names

Bono1, FKSG28, FKSG40, IGFBPrP10, KAZALD1

Entrez Gene IDs

81621 (Human); 107250 (Mouse); 293997 (Rat)

Gene Symbol

KAZALD1

UniProt

Additional IGFBP-rP10 Products

Product Documents for Human IGFBP-rP10 Biotinylated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human IGFBP-rP10 Biotinylated Antibody

For research use only

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