Human Integrin alpha4/CD49d Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB13541
Key Product Details
Species Reactivity
Human
Applications
ELISA
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # 599904
Product Specifications
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human Integrin alpha4/CD49d
Tyr34-Gln970 (Arg591Leu & Arg878Gln)
Accession # P13612
Tyr34-Gln970 (Arg591Leu & Arg878Gln)
Accession # P13612
Specificity
Detects human Integrin alpha4/CD49d in direct ELISA. In a sandwich immunoassay, this antibody detects the human Integrin alpha4 beta1 heterodimer when used with the suggested detection antibody, Mouse Anti-Human Integrin beta1 (Catalog # MAB17784).
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for Human Integrin alpha4/CD49d Antibody
Application
Recommended Usage
ELISA
This antibody functions as an ELISA capture antibody the human Integrin alpha4 beta1 heterodimer when paired with Mouse Anti-Human Integrin beta1 Monoclonal Antibody (Catalog # MAB17784).
This product is intended for assay development on various assay platforms requiring antibody pairs.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Integrin alpha 4/CD49d
The alpha4 subunit, also known as CD49d and VLA-4 alpha subunit, forms heterodimers with Integrin beta1 (CD29) or beta7. Integrins alpha4 beta1 and alpha4 beta7 are receptors for fibronectin and VCAM. Integrin alpha4 beta1 also binds the mucosal addressin cell adhesion molecule (MAdCAM-1).
Alternate Names
CD49d, ITGA4, VLA-4
Gene Symbol
ITGA4
UniProt
Additional Integrin alpha 4/CD49d Products
Product Documents for Human Integrin alpha4/CD49d Antibody
Product Specific Notices for Human Integrin alpha4/CD49d Antibody
For research use only
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