Human KIR2DS4/CD158i PE-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB1847P
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Flow Cytometry
Cited:
Flow Cytometry
Label
Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)
Antibody Source
Monoclonal Mouse IgG2A Clone # 179315
Product Specifications
Immunogen
BaF3 mouse pro-B cell line transfected with human KIR2DS4
Accession # P43632
Accession # P43632
Specificity
Detects KIR2DS4/CD158i in Western blots. In flow cytometry, this antibody stains cells transfected with KIR2DS4/CD158i. Does not stain cells transfected with KIR2DL1, 2DL2, 2DL3, 2DL4, 2DL5, 2DS1, 2DS2, 3DL1, 3DL2, or 3DS1.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Human KIR2DS4/CD158i PE-conjugated Antibody
Detection of KIR2DS4/CD158i in Human PBMCs by Flow Cytometry.
Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human KIR2DS4/CD158i PE-conjugated Monoclonal Antibody (Catalog # FAB1847P) and Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody (Catalog # FAB2408A). Quadrant markers were set based on control antibody staining (Catalog # IC003P). View our protocol for Staining Membrane-associated Proteins.Applications for Human KIR2DS4/CD158i PE-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: Human peripheral blood mononuclear cells (PBMCs)
Sample: Human peripheral blood mononuclear cells (PBMCs)
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: KIR2DS4/CD158i
KIR2DS4 is an activating immunoglobulin-like receptor expressed on NK cells and some T cells. It has been implicated in the recognition of some HLA-C alleles (1). A deletion variant encoding a single domain secreted isoform of KIR2DS4 has also been described (2).
References
- Katz, G. et al. (2001) J. Immunol. 166:7260.
- Maxwell, L. et al. (2002) Tissue Antigens 60:254.
Long Name
Killer Cell Immunoglobulin-like Receptor, Two Domains, Short Cytoplasmic Tail, 4
Alternate Names
CD158i
Entrez Gene IDs
3809 (Human)
Gene Symbol
KIR2DS4
UniProt
Additional KIR2DS4/CD158i Products
Product Documents for Human KIR2DS4/CD158i PE-conjugated Antibody
Product Specific Notices for Human KIR2DS4/CD158i PE-conjugated Antibody
For research use only
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